1Ali Raza, 2Ahmed Khan, 3Shahid Adalat Chaudhry, 4Dr. Syed Imtiaz Ali Zaidi, 5Dr. Nauman Bari Khan, 6Dr. Abaid ur Rehman, 7Kashif Lodhi
1PIMS
2Assistant Professor, Suleman Roshan Medical College Hospital Tando Adam Pakistan
3Mohi-ud-Din Islamic Medical College, Mirpur AJ & K
4Assistant Professor, Department of Anesthesiology & Intensive Care, Avicenna Medical College & Hospital, Lahore , Pakistan.
5Associate Professor, Margalla Institute of Health Sciences, Rawalpindi
6Associate Professor Anesthesia, Rashid Latif Medical College/ Hamees Latif Hospital Lahore
7Department of Agricultural, Food and Environmental Sciences. Università Politécnica delle Marche Via Brecce Bianche 10, 60131 Ancona (AN) Italy
Correspondence: Ali Raza, Assistant Professor, Suleman Roshan Medical College Hospital Tando Adam Pakistan
Abstract
Background: Pediatric patients undergoing inguinal hernia repair often experience heightened separation anxiety, which can negatively impact procedural outcomes. Preoperative sedation with oral midazolam has been proposed as a potential solution to alleviate anxiety and enhance the overall safety and efficacy of the procedure. This study aims to evaluate the efficacy and safety of preoperative oral midazolam sedation in pediatric patients undergoing inguinal hernia repair, with a specific focus on alleviating separation anxiety.
Aim: The primary aim of this study is to assess the effectiveness of preoperative oral midazolam in reducing separation anxiety among pediatric patients scheduled for inguinal hernia repair. Additionally, the study aims to evaluate the impact of midazolam sedation on procedural outcomes, including surgical success rates and postoperative recovery.
Methods: This prospective, randomized controlled trial will include pediatric patients aged 1-10 years scheduled for inguinal hernia repair. Participants will be randomly assigned to either the midazolam sedation group or the control group. The midazolam group will receive an oral dose of midazolam preoperatively, while the control group will receive a placebo. Separation anxiety levels will be assessed using standardized scales, and procedural outcomes will be meticulously recorded. Adverse events and safety parameters will also be closely monitored.
Results: The study’s results will provide insights into the efficacy of preoperative oral midazolam in reducing separation anxiety in pediatric patients undergoing inguinal hernia repair. Additionally, the impact of midazolam on procedural outcomes, including success rates and postoperative recovery, will be analyzed. Statistical analyses will be employed to compare outcomes between the midazolam group and the control group.
Conclusion: The findings of this study will contribute valuable information regarding the safety and efficacy of preoperative oral midazolam sedation in pediatric patients undergoing inguinal hernia repair. If proven effective, the integration of midazolam into preoperative protocols may offer a promising approach to mitigate separation anxiety and enhance overall procedural outcomes in this patient population.
Keywords: Pediatric surgery, inguinal hernia repair, preoperative sedation, midazolam, separation anxiety, procedural outcomes, pediatric anesthesia, safety, efficacy, randomized controlled trial.