Volume 11 Issue 10
Curative and neurological factor variations in patients with nerve entrapment, gunshot polyneuropathy, and post-traumatic non-gunshot, and plexopathies
1Dr. Shafqat Huma, 2 Dr Muhammad Ali, 3 Ali Raza, 4 Mobeen Ali , 5Umar Khan, 6Hadi raza
1Associate Professor, Department of Psychiatry, Rashid Lateef Khan University Medical College, Lahore
2 Assistant Professor, Department of Neurosurgery, People University of medical and Health Sciences for Women Nawabshah
3PIMS
4PIMS
5PIMS
6PIMS
Corresponding: Dr. Shafqat Huma, Associate Professor, Department of Psychiatry, Rashid Lateef Khan University Medical College, Lahore
| ABSTRACT: INTRODUCTION: Chronic pain adds to the patient’s already compromised life quality caused by sensory, motor, and hormonal deficiencies. Chronic pain often results from a severe injury to nerves and plexuses. It aims to examine and explain changes in neurological and immunological variables in patients experiencing plexopathies, gunshot polyneuropathy, post-traumatic non-gunshot, and compression or nerve entrapment neuropathies. METHODS: There were 93 males in the research, aged 21 to 59, who were separated into 3 groups and had plexopathy and neuropathy of both non-traumatic and traumatic origin. Beginning with the development of clinical symptoms, patients received clinical and neurological examinations as well as dynamics, electromyography, and ultrasonography. Starting at the time of the disease’s development and lasting for 12 to 24 months, an immunological investigation was conducted. RESULTS: There were statistically significant differences in the research groups’ lymphocytotoxicity, circulating immune complex concentrations, and CD4+ T cell counts. The results of the NBT test, which differentiate abruptly from zymosan-stimulated oxygen-dependent cytosis, showed that Depending on the ability of the enzymes to renew, the cells oxidized the granules of the nitroblue tetrazolium dye to different degrees. We observed a rise in the quantitative composition of the beta-NGF 303 [35.2 – 504.5] pg/ml at a clinically important level in the blood of group III patients who had chronic neuropathic pain syndrome along with plexopathies and post-traumatic gunshot neuropathies (p-value =0.0181). CONCLUSIONS: Patients who have experienced traumatic injuries to their limb nerves and plexuses benefit from knowing the features of neurotrophic and immunological control issues, how they relate to one another, and how they contribute to the emergence of chronic nerve pain in post-traumatic gunshot polyneuropathy and plexopathies. KEYWORDS: Nerve Entrapment, Polyneuropathy, Plexopathies |