Volume 9 Issue 2
Special Issue on “Medical Imaging and Image Processing”
Yudong Zhang and Zhengchao Dong
1School of Information Science and Technology, Nanjing Normal University, Nanjing, Jiangsu 210023, China
2Division of Translational Imaging & MRI Unit, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
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Author to whom correspondence should be addressed.
Abstract
2,5-Diketopiperazines (2,5-DKPs) are an important category of structurally diverse cyclic dipeptides with prominent biological properties. These 2,5-DKPs have been obtained from a variety of natural resources, including marine organisms. Because of the increasing numbers and biological importance of these compounds, this review covers 90 marine originated 2,5-DKPs that were reported from 2009 to the first half-year of 2014. The review will focus on the structure characterizations, biological properties and proposed biosynthetic processes of these compounds.
Keywords:2,5-diketopiperazine; marine organism; biosynthetic processes; biological activity